Some powders become electrostatic during the process of packed filling and readily adhere to the filling eguipment. This causes the contamination of the other powder drug which is subsequently filled by the same equipment due to difficulty in complete cleaning of the equipment. In order to prevent te adhesion of drugs to the equipment, effects of various excipients against electrification of drugs were investigated. There was no excipient which decreases electrification of any drug. It is, therefore, necessary to find out an appropriate inhibitor for each drug and to determine its optimal concentration.
Pharmacists are required to operate packaging machine carefully in order to avoid the contamination of drugs and, at the same time, drug manufacturers are much expected to provide drugs free from being electrified.
