Abstract
A simple method for measuring the volume of liquid absorbed by tablets was devised and applied to the liquid penetration test with commercialized tablets. In case of the penetration of ethyl acetoacetate, the swelling of tablets was not observed, and the V2 vs. t plots showed good linearity where V is the volume of liquid taken up. expressed in μl. and t is the time in second. In case of the water penetration, tablets swelled remarkably and the V 2 vs. t plots showed the concave lines, but the log V vs. log t plots showed a good linearity. The slopes of the regression lines obtained from the log V vs. log t plots were in the range of 0.5 to 1.0.
