病院薬学
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
ケトプロフェン注射剤と各種局所麻酔剤との配合変化
村瀬 勢津子望月 真弓朝長 文弥吉山 友二
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1986 年 12 巻 4 号 p. 333-342

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Compatibility tests on ketoprofen injection (Kp) with eight local anesthetics (LA) were performed in terms of pH, appearance, osmotic pressure against aline, and residual Kp after mixing.
For admixing, following two methods were used.
Group A: Kp is dissolved in distilled water for injection and then admixded with LA. Group B: Kp is directly dissolved in LA. The results are as follows:
1. Mixing with following drugs should be avoided:
Group A: Percamin S, Carbocain (2%), Xylocaine E (1 and 2%), Marcain (0.25 and 0.5%), Citanest (1 and 2%). Group B: Bancain (2%), Percamin S, Carbocain (2%), Xylocaine E (1 and 2%), Xylocaine (3%), Marcain (0.5, 1 and 2%).
2. Mixing with following drugs should be made with caution.
Group A: Bancain (2%), Calbocain (1%), Xylocaine (1, 2 and 3%), Xylocaine E (0.5%). Group B: Xylocaine (1 and 2%), Xylocaine E (0.5%).

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