病院薬学
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
塩化ベンザルコニウム製剤中の炭素鎖による分別定量及び綿球への吸着と品質評価
中東 正晴野田 明宏菊本 桂子野間 茂樹岩尾 勇
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1990 年 16 巻 2 号 p. 81-85

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Qualities of commercial products including benzalkonium chloride (BC) were evaluated. Amounts of C12, C14, and C16 in the commercial BC products were 66.6 to 83.3%, 10.1 to 26.2 %, and 0.0 to 3.3%, respectively.BC with C12 and C14 alkyl group is known to adsorb to a cotton ball in the monomolecular adsorption manner following the Langmuir's adsorption isotherm. The adsorption rate of C14 was larger than that of C12.
These results suggested that the preparation containing a larger amount of C12 was suitable for the clinical use.
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