病院薬学
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
高力ロリー輸液中のビタミンの安定性に及ぼす微量元素の影響
山岡 桂子中島 康雄冲永 荘一大畠 博文三宅 崇捷竹井 征夫
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1991 年 17 巻 5 号 p. 373-380

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We investigated the stability of vitamins in hyperalimentation fluids adding trace minerals. Test samples were prepared by adding trace minerals to three kinds of hyperalimentation different dextrose/electrocyte concentrations.The time-course of the potencies of vitamins and pH of the test samples with and without trace minerals were determined under three different conditions as follows: room temperature with shield or exposure of light and cold dark place. Total vitamin C content including oxidized dehydroascorbic acid was determined, and these results showed that the residual rate of the total vitamin C was decresed with the addition of trace minerals under room temperature with shield of light.The effect of the addition of trace minerals was also noted markely in the test samples under cold dark place.On the other hand, we observed no direct effect on stabilities of vitamin B1, B2, B6, folic acid, A, E, and K1, by adding trace minerals.
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