2000 年 26 巻 2 号 p. 157-163
The Ministry of Health and Welfare has issued a warning against carbapenem antibiotics regarding, their relationship to central convulsions and renal function, and also against histamine H2-receptor antagonists as well, regarding their relationship to renal dysfunction, hematological disorders, and other problems. Therefore, the careful administration of such drugs to prevent renal dysfunction is considered particularly important and strict guidelines for use of there drug have been developed but there has so far been no reports of institutional standardization of these guidelines. The Committee on the Promotion of the Appropriate Use of Medicines, which consists of physicians of various departments in our hospital, prepared unified drug administration guidelines for our hospital, and also examined their usefulness. As a result, these guidelines have proved to be useful, and were found to help reduce the overall health care costs.
