Japanese Journal of Hospital Pharmacy
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
Composition of Phenol and Zinc Oxide Liniment
Study on Availability by the Addition of Carboxymethylcellulose Sodium
BUNJI KOBO
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1983 Volume 9 Issue 5 Pages 423-430

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Abstract
For J. P. Phenol and Zink Oxide Liniment, Tragacanth, a natural product, is used as a suspending agent in the content of 5%. Its viscosity is lowered with passage of time and it is then separated. To eliminate the defects, such physical properties as viscosity, yield value, extensibility, and loss rate of water content were studied; the formula and process of manufacturing of the liniment in caption aiming at how separation and lowering of viscosity with passage of time can be prevented were examined.
It was found that a combination of 1-3% of Tragacanth and 2-4% of CMC-Na as suspending agent is adequate, and as process of manufacturing it is desirable that the mucilage is first prepared by powdered Tragacanth and CMC-Na is subsequently added. When preparing the mucilage by mixing both compounds in powder, the lowering of viscosity is remarkable.
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© Japanese Society of Pharmaceutical Health Care and Sciences
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