医療薬学
Online ISSN : 1882-1499
Print ISSN : 1346-342X
ISSN-L : 1346-342X
病院薬剤師業務のさらなる展開に向けて
外来乳癌患者における副作用自己モニタリングの試み
北田 徳昭関戸 聡子小林 睦渡 雅克折山 毅黒田 和夫
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2001 年 27 巻 3 号 p. 275-281

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In the present study, we implemented the self-monitoring of side effects in surgical outpatients with breast cancer to improve their quality of life (QOL). Self-monitoring of side effects was carried out by entering the early symptoms (myelosuppression and gastrointestinal failures) on a specially prepared side effect checking-sheet.
Six outpatients participated in this study. The chemotherapeutic regimens consisted of cyclophosphamide, adriamycin and 5-fluorouracil, i.e. CAF therapy.
In these patients, a mild myelosuppression was seen after the completion of half of each protocol (from approximately day 8 to 14). However, there was no relationship between the early symptoms of myelosuppression (“fever”, “general fatigue” and “throat pain” score) and the number of leucocytes. On the other hand, the self-monitoring of side effects showed a better influence on the subjective score for the symptoms of gastrointestinal failures (i.e. “nausea”).
In the present study, the self-monitoring of side effects in outpatients with breast cancer was thus suggested to be a useful tool for improving the patient's QOL.
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© 一般社団法人 日本医療薬学会
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