抄録
1. Acid phosphatase activity was determined biochemically in various phases of secretory activity in the rat pituitary, median eminence and anterior hypothalamus.
2. Following dehydration acid phosphatase activity increased significantly in the posterior pituitary, but no change was demonstrable in other tissues studied. Pitressin administration caused a significant reduction of the enzyme activity in the posterior pituitary and anterior hypothalamus.
3. A marked elevation in the adenohypophysial acid phosphatase was observed after 7 and 14 days of exposure to cold respectively. A similar, though less significant increase in the enzyme activity was noted in the anterior hypothalamus after 7 days of cold exposure. Chronic exposure of animals to hot ambient temperature did not affect the enzyme activity in all tissues studied.
4. Thyroidectomy as well as administration of methylthiouracil brought about a significant elevation of the phosphatase activity in the adenohypophysis. Thyroxine treatment, on the other hand, failed to affect significantly the enzyme activity.
5. Gonadectomy caused a marked enhancement of the adenohypophysial acid phosphatase, while the enzyme activity was not affected by testosterone administration.
6. Adrenalectomy did not influence the acid phosphatase activity in the anterior pituitary.
