The Japanese Journal of Physiology
Print ISSN : 0021-521X
Oxidation of Plasma Free Fatty Acids in Nonshivering Thermogenesis of Rats Treated Chronically with Norepinephrine and Thyroxine
森谷 潔小林 身哉広重 力
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1981 年 31 巻 5 号 p. 667-676

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In rats treated chronically with norepinephrine and thyroxine, enhanced nonshivering thermogenesis was observed, with a concomitant increase in the utilization of plasma free fatty acids (FFA). The increased utilization of plasma FFA was characterized by a more preferential increment in the oxidation of FFA in tissues rather than that in the uptake of FFA by tissues. These biochemical findings were accompanied by an increased mitochondrial mass in red fibers of skeletal muscle. Both biochemical and morphological changes of a similar nature were found in cold-acclimated rats.
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© Physiological Society of Japan
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