The Japanese Journal of Physiology
Print ISSN : 0021-521X
Effect of Acute Cold Exposure on ACTH and Zinc Concentrations in Human Plasma
Hideki OHNOTakehiro YAHATAKohki YAMASHITAAkihiro KUROSHIMA
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Keywords: cold exposure, ACTH, zinc
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1987 Volume 37 Issue 4 Pages 749-755

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Abstract
Effects of acute cold exposure (10°C for 60min) on the concentrations of adrenocorticotropin (ACTH) and zinc in plasma were investigated in seven healthy male students. There were no significant changes in total zinc, albumin-bound zinc, and α2-macroglobulin-bound zinc concentrations throughout the experimental period. On the other hand, ACTH concentration increased markedly during cold exposure. In addition, a statistically significant inverse relationship existed between the changes in ACTH and albumin-bound zinc values during the experiment. These results suggest that acute cold exposure produces elevated plasma ACTH levels, with resulting zinc redistribution in the human body.
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© Physiological Society of Japan
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