The Japanese Journal of Physiology
Print ISSN : 0021-521X
CONDUCTION OF NERVOUS IMPULSES IN NaCl-DEFICIENT MEDIA
上原 陽子
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ジャーナル フリー

1958 年 8 巻 p. 282-291

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Employing sciatic-peroneal nerves (desheathed) of the toad or single myelinated fibres prepared from them as material, and taking the action current as the sign of propagation, measurements were carried out among others on the critical NaCl-concentration of the bathing fluid just necessary for conduction. The observations were done on A-fibres only.
The value obtained varied from about 10% to 2% of the normal, according to the fibre size, small or large. The lowest value obtained in the case of nerve trunks turned out to be that of the largest fibres. We see from these observations that the normal Ringer solution contains NaCl in such amounts as approximately 10 to 50 times larger than the critical. The safety factor for propagation, too, was found larger in larger fibres.

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