Abstract
The nature of antifungal activity of Pseudomonas solanacearum, a pathogen of ‘bacterial wilt of the plants in the family Solanaceae and other dicotyledonous families’, was studied. Not only the wild type strains but also the mutants, which invade into the host plants but cause no symptom, were found to have antifungal activities. Microscopic observation suggested that a loss of the cellular rigidity of fungi had occurred by co-cultivations with P. solanacearum. The concentrated cell-free culture fluid of P. solanacearum specifically inhibited incorporation of 14C-glucosamine into fungal cell wall materials. These results suggest that antifungal activity in the culture fluid may be due to the inhibition of fungal cell wall synthesis.