Abstract
There are many reports on the relationships between the complaints of the patients with thyroid disease, including Graves' disease. However, Iittle information is available on described thyroid hormone levels. The present study was undertaken to determine the relations between subjective complaints and serum thyroid indicators (T_4,T_3,F-T_4,F-T_3) in patients with Graves' disease. The complaints of the patients were analyzed, according to the Cornell Medical Index (CMI). The patients with nontoxic nodular goiter served as controls. The results obtained herein were as follows : 1) Serum thyroid hormone levels of the patients with untreated Graves' disease were much higher than those of treated ones and nontoxic nodular goiter. 2) Fifty-two percent of untreated Graves' disease patients belonged to the III+IV area of Fukamachi's classification on CMI due mainly to cardiovascular complaints. There was no difference in the frequency of other somatic and psychological complaints of CMI in those three groups. 3) During T_3suppression test, serum T_3 levels of treated patients with Graves' disease were as high as those of the untreated ones. However, the frequency of their cardiovascular complaints was the same as it was before T_3 administration. The results indicate that sustained levels of increased thyroid hormone affects subjective complaints of Graves' disease patients, while the elevation of T_3 for shorter periods had without effects.
