2000 Volume 13 Issue 2 Pages 157-162
A 11-year-old girl was refered to our hospital due to continuous fever. As results of laboratory data (high titer of anti-SS-A antibody, etc), lip biopsy (infiltration of inflammatory cells into salivary grand) and sintinograhy (dysfunction of parotid and mandibular glands), she was diagnosed Sjögren syndrome. Oral predonisolone treatment (0.5 mg/kg/day) was begun. Her temperature decreased to normal and initial abnormal laboratory data was changed to normal. After 6 month, dose of predonisolone was decreased to 7.5 mg every other day. Her younger sisiter's laboratory data (anti-SS-A antibody, etc) was also abnormal. Therefore, lip biopsy and sintinography were performed. She was also diagnosed Sjögren syndrome. However, she had no clinical symptom. She was given predonisolone (1 mg/kg/day). Her laboratory data was changed to normal. After 6 month, dose of predonisolone was decreased to 7.5 mg every other day. We have experienced that oral steroid therapy for sisters suffered from Sjögren syndrome has been controlled effectively. Long period study to compare steroid therapy with other therapy for Sjögren syndrome should be done. We will try to follow their clinical condition and laboratory data continuously.
