Clinical significance of ^99mTc-DMSA renoscintigraphy for children with vesicoureteral reflux

Abstract

  We aimed to investigate, by means of dimercaptosuccinic acid (DMSA) scan, the relations between a degree of vesicoureteral reflux (VUR) and renal scar formation. Twenty-six children with VUR, 22 boys and 4 girls (mean age at the diagnosis of VUR; 67 months), were enrolled in the study.
  Results are as follows; (1) a significant correlation was found between split renal uptake in DMSA scan and grade of VUR. (2) DMSA renoscintigraphy revealed that 15% (1/6) of the kidneys with low grade VUR (I-II) and 34% (14/41) of the kidneys with high grade VUR (III-V) had renal damage. (3) Anti-reflux operation improved split renal uptake significantly.