Abstract
We report a case of Kawasaki disease in eighty six day-old-boy with grosshematuria and proteinuria after repeated treatment with a single 2g/kg dose of intravenous gamma globulin. He had no signs of renal insufficiency before repeated treatment of intravenous gamma globulin. Grosshematuria and proteinuria developed shortly after this treatment. Grosshematuria, proteinuria and microscopic hematuria disappeared 3 days, 2 weeks and 3 months after the treatment, respectively. Leukocyturia and mild proteinuria may be present in patients with Kawasaki disease, but grosshematuria and proteinuria has been rarely reported. There was no evidence of nephrotic syndrome on physical and blood examinations.We conclude that intravenous gamma globulin therapy in this patient with Kawasaki disease might have some effects on developing this renal symptoms.