Abstract
Purpose: The purpose of this study was to provide an introduction to evaluating the significance of limited exercise in IgA nephropathy.
Patients and methods: The study population consisted of thirty-eight children participating in kidney disease consultation with Kyoto City Medical Association, and sixty-six additional children admitted to Kyoto City Hospital for renal biopsy. We evaluated urine protein before and after an exercise load test, and their creatinine clearance (Ccr) changes waking and sleeping.
Results: An exercise load test showed an increase of urine protein after anexercise only in children who presented urine protein over 0.10g/gCre. Whereas, Ccr while awake was significantly higher than that of sleeping children who presented urine protein under 0.30g/gCre, there were no significant changes in sleeping children who presented urine protein over 0.30g/gCre.
Conclusion: It is possible that exercise affects kidneys with IgA nephropathy, especially where urine proteins are at high levels. Therefore, limited exercise needs to be performed as prescribed in order to prevent kidney function problems.
