抄録
OXILYZER® is a device to obtain acidic electrolyzed water from tap water. It is known that acidic water (Aqua-oxidized water) has strong bactericidal effects. We have investigated the biological safety of Aqua-oxidized water for use in the intraoral area, and three tests, hemolysis test usingrabbit blood, cytotoxicity test and mutagenicity test, were performed.
The results were as follows:
I. Aqua-oxidized water had 75% hemolysis potential even under 0.85% NaCl conditions.
2. Aqua-oxidized water showed no inhibition of cell proliferation under 25% concentration. At 25-50% concentration it showed slight inhibition, but no significant differences were observed between Aquaoxidized water and distilled water. And no change in cell morphology was observed.
3. By Salmonella/microsome mutagenicity test, Aqua-oxidized water showed no mutagenicity.
