Abstract
The tissue reaction to four implant materials inserted transcortically and extending into the medullary canal of rat tibiae was examined, and quantitative assessment of the differences in bone reaction was made using an image processing system. The materials examined were pure titanium (Ti), anodic oxidated Ti (AO-Ti), titanium alloy (Ti-6 Al-4 V), and zirconium (ZrO2). Four bioinert implant materials were progressively encapsulated with bone tissues.
Analysis revealed no significant differences among the tissue reactions to Ti, AO-Ti and Ti-6 A1-4 V.The ZrO2 implant showed the highest bone contact rate.
