塩酸ベルベリン配合義歯洗浄剤の評価に関する研究

第1報真菌に対する効果

抄録

Denture plaque is an important factor in the pathogenesis of denture stomatitis. Candida speciescan be found in high frequency in denture plaque related to denture stomatitis. This study was carried out to investigate the antifungal activity of denture cleansers with berberine hydrochloride, which has antifungal activity, againstC. albicans, C. tropicalis, and C. glabrata.
The broth dilution method was used to test the fungicidal activity of the cleansers. S 16 showed more than 99% cidal activity at 60 minutes exposure inC. albicans.S 16 was tested for the effects on Candida removal. S 16 had removed adhered fungal cells from acrylic resin surfaces approximately 64-89%.