Journal of the Japanese Physical Therapy Association
Online ISSN : 2188-8361
Print ISSN : 1344-1272
ISSN-L : 1344-1272
Short report
Effects of Treadmill Exercise on Muscle Fibers in Mice with Steroid Myopathy
Minoru OkitaToshiro YoshimuraJiro NakanoMiwako WatabeTomoko NagaiKatsutomo KatoKatsumi Eguchi
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2001 Volume 4 Issue 1 Pages 25-27

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Abstract

We studied the effect of treadmill exercise on muscle fibers in mice with experimental steroid myopathy. Frozen sections of the extensor digitorum longus (EDL) and soleus (SOL) muscles were stained with hematoxylin-eosin, and the muscle fiber diameters measured. In the EDL, muscle fiber diameters in the steroid groups decreased significantly compared with those in the control groups; moreover, muscle fiber diameters in the exercise groups increased significantly compared with those in the non-exercise groups, whereas the diameters in the SOL did not differ. We speculate that treadmill exercise may prevent corticosteroid-induced muscle fiber atrophy.

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© 2001 by the Japanese Physical Therapy Association
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