2025 Volume 14 Issue 2 Pages 57-61
We encountered an 82-year-old man who had been suffering from chest pain for two weeks before his first visit. Computed tomography revealed enlarged mediastinal lymph nodes. The soluble interleukin-2 receptor levels were elevated at 23,000U/mL, and malignant lymphoma was suspected. Endobronchial ultrasound-guided needle biopsy showed no significant findings. However, endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) revealed malignant cells, which were positive for cluster of differentiation (CD) 3 and negative for CD20 and CD79a. The patient was found to be positive for HTLV-1 antibodies and was finally diagnosed with adult T-cell leukemia/lymphoma. EBUS-IFB is useful in the diagnosis of malignant lymphoma.