Annals of the Japanese Respiratory Society
Online ISSN : 2186-5884
Print ISSN : 2186-5876
ISSN-L : 2186-5876
Case Reports
Adult T-cell leukemia/lymphoma presenting with enlarged mediastinal lymph nodes: A case report
Toshiaki Asano Mayuko IwamaTaro TanakaTomoko NishioTaeko ImamuraKoichiro Shima
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2025 Volume 14 Issue 2 Pages 57-61

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Abstract

We encountered an 82-year-old man who had been suffering from chest pain for two weeks before his first visit. Computed tomography revealed enlarged mediastinal lymph nodes. The soluble interleukin-2 receptor levels were elevated at 23,000U/mL, and malignant lymphoma was suspected. Endobronchial ultrasound-guided needle biopsy showed no significant findings. However, endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) revealed malignant cells, which were positive for cluster of differentiation (CD) 3 and negative for CD20 and CD79a. The patient was found to be positive for HTLV-1 antibodies and was finally diagnosed with adult T-cell leukemia/lymphoma. EBUS-IFB is useful in the diagnosis of malignant lymphoma.

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© 2025 The Japanese Respiratory Society
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