A case of simultaneous presence of leiomyosarcoma and squamous cell carcinoma of the esophagus

Abstract

We experienced a relatively rare case of simultaneous presence of leiomyosarcoma and squamous cell carcinoma of the esophagus. A male patient in his sixties was referred to our hospital for a close examination of esophageal tomor. Endoscopic study revealed a protruded lesion in the upper intrathoracic esophagus, and a shallow ulcer lesion at the distal side. Biopsy study revealed atypical cells in the protruded lesion, and squamous cell carcinoma in the shallow ulcer lesion. With the diagnosis of multiple cancers of the esophagus, resection of the subtotal esophagus and dissection of lymph nodes of the cervix, thorax and abdomen, and the reconstruction using a gastric roll was performed with a thoracoscopic surgery. The protruded lesion was diagnosed as leiomyosarcoma, and the shallow ulcer lesion was diagnosed as cancer of esophagus in the excised specimen. A metastasis of leiomyosarcoma appeared in the upper lobe of right lung a year after the subtotal esophagectomy and resection of the upper lobe of right lung was performed. The patient has shown no sign of recurrence after the resection of the lung for six mounths. Leiomyosarcoma of esophagus is a rare disease, and a case of simultaneous occurrence of squamous cell carcinoma is very rare, therefore we reported this case here.