A case of amputation neuroma developed with early gastric carcinoma

Abstract

A 69–year–old male complained of tarry stool during the treatment of cervical spondylotic myelopathy in another hospital. He was endoscopically diagnosed as having gastric carcinoma (tub1). A type 3 lesion was observed near the lesser curvature in the anterior wall of the upper portion of the gastric body. He underwent total gastrectomy, splenectomy, cholecystectomy and D2 lymph node dissection on December 3rd, 2004. In the resected specimen, a wide elevated lesion was observed near the lesser curvature in the anterior wall of the upper portion of the body and an elevated lesion was located on the wide elevation on the lesser curvature. Histopathologically, the former was a prominent proliferation of nerve fibers in the submucosa and was diagnosed as amputation neuroma. The latter was early gastric carcinoma (tub1, sm1, ly0, v0,n0) with U1II ulcer scar. The cause of the amputation neuroma was considered to be the damage of Meissner′s plexus by the gastric carcinoma with ulcer scar. To our knowledge, this case in the first report of the amputation neuroma developed with gastric carcinoma without any previous operation of the stomach.