Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Clinical Studies
A case of a malignant solitary fibrous tumor presented with rupture of the spleen
Takahiro SASAKISinnjiro KOBAYASHISatosi KOIZUMITaiji WATANABEHirosi NAKANOTakehito OTSUBO
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2009 Volume 70 Issue 3 Pages 859-864

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Abstract
A 29-year-old man was seen at the hospital because of abdominal pain. Abdominal CT scan showed there were large quantities of liquid pool in the abdominal cavity, the density of the spleen increased in heterogeneity, and a high absorption area was seen that seemed to be a hematoma inside of the spleen. Normal structure with contrasting effect was seen in the spleen partially, but the periphery on the lower pole aspect had ruptured and continued to the lower part. Rupture of the spleen was suggested. In addition, multiple tumor shadows were noted in the liver, and metastatic liver tumors were suspected. Because the patient had no previous history of trauma we strongly doubted rupture of the spleen due to the tumor and performed splenectomy. Nodes in various sizes were palpable on the liver surface and multiple nodules were also present on the peritoneum. During surgery, rupture of the splenic tumor, liver metastasis, peritoneal dissemination were diagnosed. The pathological diagnosis was malignant solitary fibrous tumor (MSFT), because the tumor cells wer negative for Factor VII, CD31, thrombomodulin, and S-100, while positive for CD34, alpha smooth muscle actin, and bcl-2. In this paper, we report this case of MSFT presented with splenic rupture together with some literature review.
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© 2009 Japan Surgical Association
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