Abstract
A 64-year-old female with a history of chronic rheumatoid arthritis complained of epigastralgia and diarrhea. She was found to be anemic. On barium enema images, stenosis of the transverse colon was found. Her symptoms did not improve despite the administration of TPN ; her transverse colon stenosis progressed. The transverse colon and the descending colon were excised. Mucosal edema and a widespread, large, longitudinal ulcer were found in the resected specimen. On histopathology, a diagnosis of intestinal amyloidosis was made. Amyloidosis is a relatively rare disease. However, in recent years it is becoming increasingly more frequent. There is a good association between amyloid depositions and digestive system symptoms. However, to date, very few specific symptoms or findings have been identified that are uniquely associated with large intestine involvement.
