A case of a giant malignant phyllodes tumor of the breast weighed 12.7 kg

Abstract

Giant phyllodes tumors larger than 5 kg in weight are extremely rare. We report herein a case of a 12.7 kg giant phyllodes tumor of the breast. The patient was a 52-year-old woman who developed a large left the breast tumor had skin ulceration and infection. The tumor occupied the whole left breast. She was admitted immediately because of severe anemia and malnutrition. A phyllodes tumor was suspected. A CT scan demonstrated that the tumor did not invade the chest wall and was resectaple. Simple mastectomy with skin graft was performed to control hemorrhage and infection. The resected tumor was 12.7 kg in weight and 50 cm in maximum diameter, and the histological diagnosis of malignant phyllodes tumor was made. The Ki-67 index was more than 50%. She has not experienced either local recurrence or distant metastasis up to now.
This paper presents our case and a review of 9 cases of giant phyllodes tumor of the breast reported in the Japanese literature.