Abstract
A 50-year-old female presented on May 2008 with an abnormal discharge from the left nipple that she first noticed a year earlier. The findings of magnetic resonance imaging (MRI), the cytological examination, and the needle biopsy did not help establish a definite diagnosis. Therefore, the patient was followed. At the end of July 2008, the patient requested to be evaluated further. Mammography revealed a cluster of pleomorphic, calcified lesions extending from the left nipple to the lactiferous sinus. The MRI scan showed a funicular, high-intensity area in the nipple. Ultrasonographic examination of the mammary glands showed an irregular, hypoechoic area in the right breast. Ductal carcinoma in situ (DCIS) was diagnosed on needle biopsy. Breast-conservation surgery with sentinel lymph node biopsy of the right breast and microdochectomy of the left breast were performed. Histopathological examination revealed DCIS in both breasts ; DCIS of the left breast was localized to the lactiferous ducts located at the nipple. Since ductal carcinoma of the nipple is very rare, we present the case report along with a review of the relevant literature.
