Abstract
Acromegaly is a relatively rare disorder characterized by excessive secretion of the growth hormone by the pituitary adenoma. Recent reports suggest that malignant tumors such as those in the large intestine, mammary gland, and prostatic gland develop concomitantly. Here in, we report the case of a 71-year-old female who underwent Hardy's operation for acromegaly and pituitary adenoma at the age of 59. Of her own accord, she stopped visiting the hospital after surgery. Because she observed bleeding during bowel movements, she visited a nearby doctor. Hemorrhoids were detected and she underwent treatment, however, because the symptoms persisted, she underwent a detailed gastrointestinal tract examination that revealed a type 1 tumor in the sigmoid colon and was consequently referred to our department for treatment. Only diffuse thyroid gland enlargement was observed upon close systemic examination and no metastatic findings were observed. Sigmoidectomy was performed, the patient showed good recovery thereafter. Endocrine function tests indicated high growth hormone and Insulin-like growth factor levels ; sigmoid colon cancer had developed with acromegaly because of insufficient inhibition of excessive secretion of growth hormone after the resection of the pituitary adenoma. The administration of bromocriptine was initiated and she was followed as an outpatient.
