Abstract
A 52-year-old woman was presented with headache, dizziness and agnosia. Multiple brain lesions up to 6 cm in diameter were detected by cranial magnetic resonance imaging (MRI) and were suspected to be metastatic brain tumors. Thoracoabdominal computed tomography (CT) scan indicated a tumor 6 cm in diameter accompanied with coarse carcification on the right breast and ipsilateral axillary and supraclavicular lymphadenopathy. This tumor had been followed as an old fibroadenoma for 32 years, and mammography and ultrasonography revealed no malignant finding ; while contrast breast MRI detected it as an enhanced tumor which is a rare finding with an old fibroadenoma. Pathology of the removed brain tumor revealed metastatic adenocarcimona, and subsequent core needle biopsy identified breast cancer. Therefore, the breast tumor was excited, and finally brain metastasis from the invasive ductal adenocarcoma originated in the old FA, both of which were hormone receptor negative, HER2-negative. Breast cancer arising in fibroadenoma is rare and to the best of our knowledge, this is the first case diagnosed from brain metastasis.
