Abstract
Synchronous double cancer involving multiple myeloma and gastrointestinal cancer is relatively rare. The patient was a 53-year-old man. An S-shaped colon cancer was found, and he was referred for surgery. A laparoscopy-assisted high anterior resection was done. On the fourth day after operation, the patient developed a fever of 38 °C and pancytopenia was present ; all of his medications were discontinued since a drug-related disorder was suspected. Two months after surgery, the patient was readmitted with abdominal pain and general malaise. Dynamic CT showed multiple low density areas in the thoracic spine, lumbar spine, and pelvic bone ; multiple myeloma was diagnosed based on the presence of Bence Jones protein in the urine. When mild proteinuria and anemia are noted at the time of the initial preoperative examination, the patient should be evaluated for the presence of bone lesions and perioperative management should take this condition into account.