Abstract
The patient was a 50-year-old woman, who received a left colorectomy for decending colon cancer and multiple liver metastases. Neoadjuvant chemotherapy with mFOLFOX6 and Bevacizumab was performed for liver metastases. After neoadjuvant chemotherapy, PR was proved on the RECIST standard and left lateral sectionectomy, a partial resection of the liver and cholecystectomy was performed. Pathological findings of the S5 segment revealed no viable cancer cells. The histological effect of neoadjuvant chemotherapy was grade 3. After 8 courses of the neoadjuvant chemotherapy, the huge liver metastasis 6.5 cm in diameter, was a pathological CR. The bulky liver metastasis that had not ever been reported vanished after neoadjuvant chemotherapy. We expected that neoadjuvant chemotherapy with a molecularly targeted drug would increase the cases of resectable liver metastasis.
