Abstract
A 59-year-old woman admitted for fever and general fatigue was found to have a clear-margined mass at the lower part of the bile duct using computed tomography (CT) and magnetic resonance imaging (MRI). Endoscopic retrograde cholangiography showed a tumor occupying the lower part of the bile duct, and brushing cytology indicated small cell carcinoma of the bile duct. We performed subtotal stomach preserving pancreaticoduodenectomy and lymph nodes dissection under a diagnosis of small cell carcinoma of the bile duct. Finally we diagnosed it as small cell carcinoma of the common bile duct by pathological studies and immunohistochemical analysis. We administered cisplatin/etoposide as an adjuvant chemotherapy for four course based on the regimen of small cell carcinoma of the lung. The patient has been alive for 23 months without recurrence.
