Abstract
Intraductal papillary neoplasm of the bile duct (IPN-B) is characterized by its pathological similarity to intraductal papillary mucinous neoplasms of pancreas (IPMN). We report a case of IPN-B which recurred 4 years after primary resection. A 76-year-old woman who presented with mild liver dysfunction was diagnosed as IPN-B in the hepatic hilum. We performed a left hepatectomy, caudate lobectomy, and extrahepatic bile duct resection. Histologically, the tumor was identified as non-invasive papillary adenocarcinoma, and it showed neither flat superficial spread nor invasion of the bile duct margins. Four years later, recurrence was found at the intrapancreatic portion of the bile duct on regular CT scanning. We performed a subtotal stomach-preserving pancreaticoduodenectomy. Long-term follow-up examination, such as CT scanning is necessary considering that IPN-B has a potential for recurrence after curative resection.