Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Case Reports
A Case of Pneumatosis Cystoides Intestinalis with Hepatic Portal Venous Gas Induced by α-Glucosidase Inhibitor
Kuniyuki KATO, Kentaro FUJISAWA, Yoshiyuki TAMASAWA, Shingo MITOMO, Masahiro SASE, Go WAKABAYASHI
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2013 Volume 74 Issue 6 Pages 1557-1562

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Abstract
A 74-year-old woman was brought into our hospital because of abdominal distension after an enema administration. Abdominal CT scan showed free air, hepatic portal venous gas, and pneumatosis cystoides intestinalis in the wall of the small intestine. There were no apparent findings suggestive of intestinal necrosis and gastrointestinal perforation. The patient's condition improved through conservative therapy including withdrawal of an α-glucosidase inhibitor for diabetes. Recentely pneumatosis cystoides intestinalis caused by α-glucosidase inhibitors has sometimes been reported. We consider that an α-glucosidase inhibitor might induce pneumatosis cystoides intestinalis in this case. Abrupt elevation of the inner pressure in the intestine due to the enema might cause rupture of emphysema, transference of gas into the vessel, and resultant free air and hepatic portal venous gas.
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© 2013 Japan Surgical Association
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