A Case of a Recurred Fibroadenoma which Had DCIS Diffusely and Grew Rapidly

Abstract

A 41-year-old woman was found having a 110×60 mm fibroadenoma showing an enlarging tendency in the C area of the left breast and underwent the resection of the fibroadenoma. The histopathological diagnosis was fibroadenoma in which stroma and epithelium had proliferated, nuclear atypia was scarce, and malignant findings were absent. Echography of the breast peformed six months after the operation revealed a 6 × 4 mm newly appeared tumor at the previously resected area. The tumor size was kept unchanged for eight months, but it rapidly grew to 45 × 30 mm in size during the subsequent three months. A fine needle biopsy cytology indicated the tumor to be recurrence of the fibroadenoma, and it was removed under local anesthesia. The final pathological diagnosis was fibroadenoma involving ductal carcinoma in situ (DCIS). The tumor cells had solidly grown within the mammary duct, but DCIS remained within the fibroadenoma which had a capsule. We determined that the lesion was able to be removed completely by the biopsy and no additional resection was done. After the operation we gave oral tamoxifen and irradiation therapy for the affected breast.
This paper deals with a case of a recurred fibroadenoma which arose in the surgical area of the primary fibroadenoma as large as 110 mm in diameter, had DCIS diffusely, and grew rapidly within the capsule.