A Case of Resected Primary Hepatic Neuroendocrine Cell Carcinoma

Abstract

A 74-year-old woman presented with obstructive jaundice and was referred to our hospital, as perihilar cholangiocarcinoma was suspected. We performed extended right hepatectomy with regional lymphadenectomy and resection of the extrahepatic bile duct and portal vein. Pathological findings revealed neuroendocrine cell carcinoma G3 (World Health Organization classification, 2010). No other lesions were detected by intraoperative findings or preoperative examinations such as gastroenterological endoscopy, computed tomography, and magnetic resonance imaging ; therefore, primary hepatic neuroendocrine carcinoma was diagnosed. The patient showed recurrence with multiple liver metastases four months after the operation, and now receives chemotherapy.
Primary neuroendocrine tumor of the liver is an extremely rare disease. Here, we report a rare case of primary hepatic neuroendocrine cell carcinoma and review the current literature.