Abstract
A 75-year-old man underwent a right lower lobectomy with nodal dissection (ND2a-2)for Stage I A primary lung cancer. He was administered loxoprofen as pain control from post operative day (POD)1. Dry cough, shortness of breath with effort, and hypoxemia were noted on POD12 and a fine crackle in his back was audible. Transbronchial lung biopsy findings revealed eosinophil infiltration in the alveolar septum and loxoprofen was positive in a drug-induced lymphocyte stimulation test. The patient was diagnosed with drug-induced eosinophilic pneumonia caused by loxoprofen and the drug was stopped, which led to gradual recovery without steroid administration. Drug-induced eosinophilic pneumonia should be checked following surgery when a patient develops a dry cough and shortness of breath, along with diffuse infiltration shown in chest X-ray images.
