Abstract
A 74-year-old woman was seen in our department for a right chest wall lump, which had been noticed a few days earlier. Physical examination revealed a palpable mass with restricted mobility. Computed tomography (CT) examination showed a nodular mass in the chest wall. We suspected a local recurrence or distant metastasis to the chest wall of a primary tumor because the patient had a history of right breast cancer and cecal cancer, both of which had been surgically treated. Positron emission tomography with fluorodeoxyglucose (FDG-PET) examination showed abnormal FDG accumulation in the lesion. The patient underwent tumorectomy under local anesthesia. The tumor had infiltrated the subcutaneous tissue and the muscle layer. It was a solid mass, milky-white and grayish-white in color, measuring 1.8 × 1.5 × 1.2 cm with a distinct margin.
Histopathological examination showed spindle cell proliferation with abundant inflammatory cells. Immunohistochemical staining showed the tumor cells to be positive for vimentin and alpha-smooth muscle actin, and negative for S-100 and c-kit. It was then diagnosed as an inflammatory myofibroblastic tumor. To the best of our knowledge, this is the first case report of inflammatory myofibroblastic tumor originating from the subcutaneous chest wall.
