Abstract
A 52-year-old woman who complained of epigastralgia, backache, and anorexia was referred to our hospital. Abdominal computed tomography revealed a 14-cm hypervascular, lobulated tumor in the whole pancreas. A filling defect suspected to be a tumor thrombus was observed in the splenic and omental veins. In addition, tumor infiltration into the superior mesenteric vein, left renal vein, and left adrenal gland was suspected. We made a diagnosis of pancreatic neuroendocrine tumor and performed total pancreatectomy with lymph node dissection. We also resected the portal vein, left adrenal gland, and left kidney. Pathohistological examination revealed that the tumor was an acinar cell carcinoma of the pancreas. The postoperative course was generally uneventful. Although no recurrence was found 14 months later, continuous careful follow-up was necessary.