Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Case Reports
A Long-surviving Case of Alpha-fetoprotein Producing Gastric Cancer after Resection of Liver and Lung Metastases and Radiofrequency Ablation
Yoshiyuki YAMAMURAKazufumi UMEMOTOTomohiro SUZUKITatsuya YOSHIOKAKatsuhiko MURAKAWAKoichi ONO
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2015 Volume 76 Issue 5 Pages 1025-1030

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Abstract
A 74-year-old man underwent total gastrectomy for gastric cancer, when the histopathological diagnosis was Stage IB gastric cancer. Twenty-three months later, he underwent two courses of TS-1 + CDDP followed by a partial hepatectomy for hepatic metastasis in S5. Histopathological findings revealed the primary gastric cancer to be alpha-fetoprotein (AFP) producing gastric cancer. Thirty-three months after the gastrectomy (or five months after hepatectomy) a tumor in the right lung (S3) was found on a chest CT scan, for which paclitaxel (PTX) was ineffective. Forty-four months after the gastrectomy, he underwent pulmonary resection for the lung metastasis. The histopathological diagnosis was pulmonary metastasis of AFP-producing gastric cancer. Fifty-three months after gastrectomy (or 25 months after hepatectomy or 10 months after pulmonary resection), he had transcatheter arterial embolization (TAE) combined with radiofrequency ablation (RFA) for hepatic metastasis in S8. Thereafter he has been followed in our outpatient clinic, and as of 120 months after resection of the primary gastric cancer, he is alive without recurrence.
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© 2015 Japan Surgical Association
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