Abstract
A 64-year-old man who underwent PET/CT for cancer screening was found to show accumulation of FDG at the appendiceal orifice. Colonoscopy showed a small protrusion at the appendiceal orifice, and a biopsy revealed findings of colitis. A second colonoscopy performed 6 months after the first revealed a reddish, mulberry-like polyp measuring 2 cm in diameter at the appendiceal orifice. The repeat biopsy also showed colitis. A laparoscopy-assisted ileocecal resection was performed. In the resected specimen, the polyp had disappeared, and only a dark red protrusion measuring 2 mm in diameter was found. The histopathological diagnosis was lymphoid hyperplasia at the appendiceal orifice. Lymphoid hyperplasia is common at the end of the ileum. However, solitary nodular lymphoid hyperplasia at the appendiceal orifice increasing or decreasing in size during follow-up is rare.
