Abstract
We report a case of breast carcinoma containing a micropapillary component (mixed micropapillary ductal carcinoma) in a man. A 62-year-old man presented with a 2.5 cm mass in his left breast, which was diagnosed as mixed micropapillary ductal carcinoma after a core needle biopsy, and a 2.5 cm mass in his left axilla. The tumor biomarker statuses were as follows : estrogen receptor, positive ; progesterone receptor, positive ; human epidermal growth factor receptor-2 expression, negative ; and Ki67 index, 16%. He was treated with neoadjuvant chemotherapy followed by mastectomy with axillary lymph node dissection. The pathological findings showed that most of the viable tumor cells had disappeared. He was prescribed adjuvant tamoxifen for 2 years and did not show any signs of recurrence. Although luminal A-like breast cancer and micropapillary carcinoma have been reported to have poor responsiveness to chemotherapy, this case showed an excellent response to neoadjuvant chemotherapy. There are few reports on neoadjuvant chemotherapy for male breast cancer ; however, it could be a valuable treatment choice for men, similar to its use for women at high risk.
