Abstract
A 36-year-old-woman was referred to our hospital with a retroperitoneal mass detected by a screening computed tomography (CT) scan. The mass measuring 8.5 cm in size was located near the hilum of the left kidney with enlarged lymph nodes around it. The patient presented with anemia, splenomegaly, and ascites. A CT-guided needle biopsy could not establish a pathologic diagnosis. Tumor resection was performed, and she was diagnosed as having hyaline vascular type-Castleman's disease with several peripheral para-aortic nodes showing typical characteristics of Castleman's disease. A diagnosis of unicentric-Castleman's disease was made because the involved enlarged lymph nodes were localized in this region. Her anemia and splenomegaly improved 10 months after operation, and ascites had resolved. This case showed that surgical resection might help improve systemic symptoms such as anemia, splenomegaly, and ascites noted with unicentric-Castleman's disease.
