Abstract
Objectives : Recently chronic kidney disease (CKD) has received attention as a risk factor of perioperative complications. This study was made to elucidate the impact of CKD on the outcomes of hepatectomy for hepatocellular carcinoma (HCC).
Methods : This study enrolled a total of 240 patients with HCC undergone hepatectomy in our hospital from 2011 to 2015. Sixty-three patients whose estimated glomerular filtration rates (eGFR) were under 60 mL/min/l.73 m2 were classified into the CKD group and the remaining 177 patients whose eGFRs were over 60 were served as control (the control group) ; and their background factors, surgery-relating factors and perioperative complications were compared between the both groups.
Outcomes : Perioperative complications more than Grade III according to the Clavien-Dindo classification occurred in 11.1% of the patients from the CKD group and 13.1% of the control group, without statistically significant difference. There were no significant differences between them in the perioperative mortality, frequencies of cardiovascular complications, postoperative acute renal impairment, and surgical wound infection.
Conclusion : Compared to non-CKD patients, hepatectomy for CKD patients with HCC could be performed without associating significant increases in frequencies of postoperative complications.
