Abstract
Objective : To evaluate the usefulness of early oral intake and goal directed fluid therapy (GDT) in enhanced recovery after surgery (ERAS) for pancreaticoduodenectomy (PD).
Methods : The records of 107 patients who underwent PD in our hospital were enrolled in this retrospective study. They were divided into the ERAS group (48 patients) and the conventional group (59) to compare for the volume of infusion, complication rate and length of hospital stay, and oral intake in the ERAS group was examined.
Results : The rate of patients who achieved oral intake of half or more in the ERAS group was 72.9% on the 3rd postoperative day. Intraoperative infusion balance decreased in the ERAS group (+ 3844 ml vs + 2637 ml, p <0.001). Postoperative complication rate was 55.9% in the conventional group versus 39.6% in the ERAS group (p = 0.64), and the length of postoperative hospital stay was 18 days versus 17 days (p = 0.28), respectively, without significant differences.
Conclusion : Introduction of ERAS protocols into PD could safely achieve the early oral intake and the optimization of intraoperative fluid volume by GDT, though clinical usefulness of early oral intake and GDT was obscure.
