Abstract
Ductal carcinoma in situ (DCIS) increases yearly. Recently, the pathological findings of DCIS are considered important in the management of DCIS. Eighty-four patients with DCIS underwent mammography, ultrasound, and core needle biopsy, and their diagnoses were confirmed on the basis of pathological findings after surgery. Ultrasonographic findings of DCIS were classified into 6 patterns according to the guideline of the Japan Association of Breast and Thyroid Sonology (JABTS). The correlation between ultrasonographic and pathological findings of DCIS were investigated. The ultrasonographic patterns in 84 cases of DCIS showed 40 solid mass (type 1), 3 intracystic mass (type 2), 12 intraductal mass (type 3), 28 hypoechoic area in the mammary gland (type 4), and 1 multiple small cysts (type 5) patterns. In the correlation between ultrasonography patterns and nuclear grade (Grade), Grade 1 in type 1 accounted for 80% and Grade 2 and 3 in type 1 accounted for 20%. In contrast, Grade 2 and 3 in type 4 accounted for 50%, and Grade 3 of Grade 2 and 3 in type 4 accounted for 43%. In the correlation between ultrasonography patterns and Ki67 status, the cases of over 20% Ki67 level were 21% in type 1 and 44% in type 4. According to nuclear grade and Ki67 status, type 1 showed a higher rate of low grades than type 4. In particular, DCIS with calcification showed a higher rate of non-low grade than DCIS without calcification.
