Malakoplakia of the Appendix—A Case Report—

Abstract

A 56-year-old man was diagnosed with acute appendicitis in January 2016. He initially refused surgery and underwent conservative management. However, in March 2017, he underwent laparoscopic appendectomy. Histopathological examination of resected specimens revealed granuloma formation in the appendiceal lumen. Hematoxylin-eosin stained specimens showed Michaelis-Gutmann bodies with a target-like appearance. Notably, periodic acid-Schiff stained specimens also showed the same findings. Thus, the patient was diagnosed with malakoplakia. Malakoplakia is an inflammatory granulomatous disease occurring primarily in the genitourinary tract. This disease occurs in patients with underlying conditions such as an immunocompromised state or malignancy. We report a rare case of malakoplakia of the appendix and additionally present a short literature review.