A Case of Gallbladder Carcinoma with Bleeding after Starting Anticoagulant Therapy

Abstract

Several cases of gallbladder bleeding with anticoagulation therapy have been documented, but cases involving gallbladder carcinoma are rare. We herein present a case of gallbladder carcinoma with bleeding after the commencement of anticoagulant therapy. An 84-year-old male patient with dysarthria disorder and right hemiplegia was admitted on an emergency basis. He had been receiving anticoagulation therapy for treating a cardiogenic cerebral infarction. On hospital day 3, he began experiencing abdominal pain. Abdominal computed tomography revealed findings suggestive of gallbladder hemorrhage. A laparoscopic cholecystectomy was performed but was converted to open surgery because of severe hemorrhage. Gallbladder carcinoma (T1b) and positive margins of the cystic duct were histopathologically confirmed. Extrahepatic bile duct resection, hepaticojejunostomy, and regional lymph node dissection were additionally performed. The patient was discharged on hospital day 58 with no postoperative complications.